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Safety Evaluation of Hemoglobin-Albumin Cluster “HemoAct” as a Red Blood Cell Substitute

A hemoglobin (Hb) wrapped covalently by human serum albumins (HSAs), a core–shell structured hemoglobin-albumin cluster designated as “HemoAct”, is an O(2)-carrier designed for use as a red blood cell (RBC) substitute. This report describes the blood compatibility, hemodynamic response, and pharmaco...

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Detalles Bibliográficos
Autores principales: Haruki, Risa, Kimura, Takuya, Iwasaki, Hitomi, Yamada, Kana, Kamiyama, Ikuo, Kohno, Mitsutomo, Taguchi, Kazuaki, Nagao, Saori, Maruyama, Toru, Otagiri, Masaki, Komatsu, Teruyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518235/
https://www.ncbi.nlm.nih.gov/pubmed/26220366
http://dx.doi.org/10.1038/srep12778