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Safety Evaluation of Hemoglobin-Albumin Cluster “HemoAct” as a Red Blood Cell Substitute
A hemoglobin (Hb) wrapped covalently by human serum albumins (HSAs), a core–shell structured hemoglobin-albumin cluster designated as “HemoAct”, is an O(2)-carrier designed for use as a red blood cell (RBC) substitute. This report describes the blood compatibility, hemodynamic response, and pharmaco...
Autores principales: | Haruki, Risa, Kimura, Takuya, Iwasaki, Hitomi, Yamada, Kana, Kamiyama, Ikuo, Kohno, Mitsutomo, Taguchi, Kazuaki, Nagao, Saori, Maruyama, Toru, Otagiri, Masaki, Komatsu, Teruyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518235/ https://www.ncbi.nlm.nih.gov/pubmed/26220366 http://dx.doi.org/10.1038/srep12778 |
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