A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus

Effective annual influenza vaccination requires frequent changes in vaccine composition due to both antigenic shift for different subtype hemagglutinins (HAs) and antigenic drift in a particular HA. Here we present a broadly neutralizing human monoclonal antibody with an unusual binding modality. Th...

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Detalles Bibliográficos
Autores principales: Wu, Ying, Cho, MyungSam, Shore, David, Song, Manki, Choi, JungAh, Jiang, Tao, Deng, Yong-Qiang, Bourgeois, Melissa, Almli, Lynn, Yang, Hua, Chen, Li-Mei, Shi, Yi, Qi, Jianxu, Li, An, Yi, Kye Sook, Chang, MinSeok, Bae, Jin Soo, Lee, HyunJoo, Shin, JiYoung, Stevens, James, Hong, SeoungSuh, Qin, Cheng-Feng, Gao, George F., Chang, Shin Jae, Donis, Ruben O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518248/
https://www.ncbi.nlm.nih.gov/pubmed/26196962
http://dx.doi.org/10.1038/ncomms8708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518248/
https://www.ncbi.nlm.nih.gov/pubmed/26196962
http://dx.doi.org/10.1038/ncomms8708

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