Cargando…
Large-scale genomics unveil polygenic architecture of human cortical surface area
Little is known about how genetic variation contributes to neuroanatomical variability, and whether particular genomic regions comprising genes or evolutionarily conserved elements are enriched for effects that influence brain morphology. Here, we examine brain imaging and single-nucleotide polymorp...
Autores principales: | Chen, Chi-Hua, Peng, Qian, Schork, Andrew J., Lo, Min-Tzu, Fan, Chun-Chieh, Wang, Yunpeng, Desikan, Rahul S., Bettella, Francesco, Hagler, Donald J., Westlye, Lars T., Kremen, William S., Jernigan, Terry L., Hellard, Stephanie Le, Steen, Vidar M., Espeseth, Thomas, Huentelman, Matt, Håberg, Asta K., Agartz, Ingrid, Djurovic, Srdjan, Andreassen, Ole A., Schork, Nicholas, Dale, Anders M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518289/ https://www.ncbi.nlm.nih.gov/pubmed/26189703 http://dx.doi.org/10.1038/ncomms8549 |
Ejemplares similares
-
Conservation of Distinct Genetically-Mediated Human Cortical Pattern
por: Peng, Qian, et al.
Publicado: (2016) -
Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder
por: Tesli, Martin, et al.
Publicado: (2015) -
Williams Syndrome neuroanatomical score associates with GTF2IRD1 in large-scale magnetic resonance imaging cohorts: a proof of concept for multivariate endophenotypes
por: Fan, Chun Chieh, et al.
Publicado: (2018) -
MicroRNAs enrichment in GWAS of complex human phenotypes
por: Goulart, Luiz F, et al.
Publicado: (2015) -
Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data
por: Polushina, Tatiana, et al.
Publicado: (2017)