Intestinal CD169(+) macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

Lamina propria (LP) macrophages are constantly exposed to commensal bacteria, and are refractory to those antigens in an interleukin (IL)-10-dependent fashion. However, the mechanisms that discriminate hazardous invasion by bacteria from peaceful co-existence with them remain elusive. Here we show t...

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Detalles Bibliográficos
Autores principales: Asano, Kenichi, Takahashi, Naomichi, Ushiki, Mikiko, Monya, Misa, Aihara, Fumiaki, Kuboki, Erika, Moriyama, Shigetaka, Iida, Mayumi, Kitamura, Hiroshi, Qiu, Chun-Hong, Watanabe, Takashi, Tanaka, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518321/
https://www.ncbi.nlm.nih.gov/pubmed/26193821
http://dx.doi.org/10.1038/ncomms8802

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