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Active suppression of intestinal CD4(+)TCRαβ(+) T-lymphocyte maturation during the postnatal period
Priming of the mucosal immune system during the postnatal period substantially influences host–microbial interaction and susceptibility to immune-mediated diseases in adult life. The underlying mechanisms are ill defined. Here we show that shortly after birth, CD4 T cells populate preformed lymphoid...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518322/ https://www.ncbi.nlm.nih.gov/pubmed/26195040 http://dx.doi.org/10.1038/ncomms8725 |