Interplay between Nonsense-Mediated mRNA Decay and DNA Damage Response Pathways Reveals that Stn1 and Ten1 Are the Key CST Telomere-Cap Components

A large and diverse set of proteins, including CST complex, nonsense mediated decay (NMD), and DNA damage response (DDR) proteins, play important roles at the telomere in mammals and yeast. Here, we report that NMD, like the DDR, affects single-stranded DNA (ssDNA) production at uncapped telomeres....

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Detalles Bibliográficos
Autores principales: Holstein, Eva-Maria, Clark, Kate R.M., Lydall, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518466/
https://www.ncbi.nlm.nih.gov/pubmed/24835988
http://dx.doi.org/10.1016/j.celrep.2014.04.017

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