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The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity
Identifying the molecular mechanisms that underlie aging and their pharmacological manipulation are key aims for improving lifelong human health. Here, we identify a critical role for Ras-Erk-ETS signaling in aging in Drosophila. We show that inhibition of Ras is sufficient for lifespan extension do...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518474/ https://www.ncbi.nlm.nih.gov/pubmed/26119340 http://dx.doi.org/10.1016/j.cell.2015.06.023 |