Cargando…
Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis
The role of intestinal eosinophils in immune homeostasis is enigmatic and the molecular signals that drive them from protective to tissue damaging are unknown. Most commonly associated with Th2 cell-mediated diseases, we describe a role for eosinophils as crucial effectors of the interleukin-23 (IL-...
Autores principales: | Griseri, Thibault, Arnold, Isabelle C., Pearson, Claire, Krausgruber, Thomas, Schiering, Chris, Franchini, Fanny, Schulthess, Julie, McKenzie, Brent S., Crocker, Paul R., Powrie, Fiona |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518500/ https://www.ncbi.nlm.nih.gov/pubmed/26200014 http://dx.doi.org/10.1016/j.immuni.2015.07.008 |
Ejemplares similares
-
Dysregulated Hematopoietic Stem and Progenitor Cell Activity Promotes Interleukin-23-Driven Chronic Intestinal Inflammation
por: Griseri, Thibault, et al.
Publicado: (2012) -
OX40 is required for regulatory T cell–mediated control of colitis
por: Griseri, Thibault, et al.
Publicado: (2010) -
T-bet is a key modulator of IL-23-driven pathogenic CD4(+) T cell responses in the intestine
por: Krausgruber, Thomas, et al.
Publicado: (2016) -
Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling
por: Ilott, Nicholas Edward, et al.
Publicado: (2016) -
Interleukin-23 drives innate and T cell–mediated intestinal inflammation
por: Hue, Sophie, et al.
Publicado: (2006)