Detection of KRAS, NRAS and BRAF by mass spectrometry - a sensitive, reliable, fast and cost-effective technique

BACKGROUND: According to current clinical guidelines mutational analysis for KRAS and NRAS is recommended prior to EGFR-directed therapy of colorectal cancer (CRC) in the metastatic setting. Therefore, reliable, fast, sensitive and cost-effective methods for routine tissue based molecular diagnostic...

Descripción completa

Detalles Bibliográficos
Autores principales: Kriegsmann, Mark, Arens, Norbert, Endris, Volker, Weichert, Wilko, Kriegsmann, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518505/
https://www.ncbi.nlm.nih.gov/pubmed/26220423
http://dx.doi.org/10.1186/s13000-015-0364-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518505/
https://www.ncbi.nlm.nih.gov/pubmed/26220423
http://dx.doi.org/10.1186/s13000-015-0364-3

Ejemplares similares