Tuberous sclerosis complex neuropathology requires glutamate-cysteine ligase

INTRODUCTION: Tuberous sclerosis complex (TSC) is a genetic disease resulting from mutation in TSC1 or TSC2 and subsequent hyperactivation of mammalian Target of Rapamycin (mTOR). Common TSC features include brain lesions, such as cortical tubers and subependymal giant cell astrocytomas (SEGAs). How...

Descripción completa

Detalles Bibliográficos
Autores principales: Malik, Anna R., Liszewska, Ewa, Skalecka, Agnieszka, Urbanska, Malgorzata, Iyer, Anand M., Swiech, Lukasz J., Perycz, Malgorzata, Parobczak, Kamil, Pietruszka, Patrycja, Zarebska, Malgorzata M., Macias, Matylda, Kotulska, Katarzyna, Borkowska, Julita, Grajkowska, Wieslawa, Tyburczy, Magdalena E., Jozwiak, Sergiusz, Kwiatkowski, David J., Aronica, Eleonora, Jaworski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518593/
https://www.ncbi.nlm.nih.gov/pubmed/26220190
http://dx.doi.org/10.1186/s40478-015-0225-z

Ejemplares similares

Ejemplares similares