Voluntary exercise attenuates LPS-induced reductions in neurogenesis and increases microglia expression of a proneurogenic phenotype in aged mice

BACKGROUND: Microglia can acquire various phenotypes of activation that mediate their inflammatory and neuroprotective effects. Aging causes microglia to become partially activated towards an inflammatory phenotype. As a result, aged animals display a prolonged neuroinflammatory response following a...

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Detalles Bibliográficos
Autores principales: Littlefield, Alyssa M., Setti, Sharay E., Priester, Carolina, Kohman, Rachel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518639/
https://www.ncbi.nlm.nih.gov/pubmed/26224094
http://dx.doi.org/10.1186/s12974-015-0362-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518639/
https://www.ncbi.nlm.nih.gov/pubmed/26224094
http://dx.doi.org/10.1186/s12974-015-0362-0

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