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Downregulation of dystroglycan glycosyltransferases LARGE2 and ISPD associate with increased mortality in clear cell renal cell carcinoma

BACKGROUND: Dystroglycan (DG) is a cell-surface laminin receptor that links the cytoskeleton to the extracellular matrix in a variety of epithelial tissues. Its function as a matrix receptor requires extensive glycosylation of its extracellular subunit αDG, which involves at least 13 distinct genes....

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Detalles Bibliográficos
Autores principales:	Miller, Michael R., Ma, Deqin, Schappet, James, Breheny, Patrick, Mott, Sarah L., Bannick, Nadine, Askeland, Eric, Brown, James, Henry, Michael D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518861/ https://www.ncbi.nlm.nih.gov/pubmed/26220087 http://dx.doi.org/10.1186/s12943-015-0416-z

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