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Crystal structure of N-[(morpholin-4-yl)(thiophen-2-yl)methyl]benzamide
In the title compound, C(16)H(18)N(2)O(2)S, the morpholine ring adopts a chair conformation. The thiophene ring makes a dihedral angle of 63.54 (14)° with the mean plane of the four C atoms [maximum deviation = 0.010 (3) Å] of the morpholine ring. The benzamide ring is disordered, with four C atoms...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518906/ https://www.ncbi.nlm.nih.gov/pubmed/26279929 http://dx.doi.org/10.1107/S2056989015011639 |
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author | Prabhu, S. Arun Suresh, M. Jameel, A. Abdul Padusha, M. Syed Ali Gunasekaran, B. |
author_facet | Prabhu, S. Arun Suresh, M. Jameel, A. Abdul Padusha, M. Syed Ali Gunasekaran, B. |
author_sort | Prabhu, S. Arun |
collection | PubMed |
description | In the title compound, C(16)H(18)N(2)O(2)S, the morpholine ring adopts a chair conformation. The thiophene ring makes a dihedral angle of 63.54 (14)° with the mean plane of the four C atoms [maximum deviation = 0.010 (3) Å] of the morpholine ring. The benzamide ring is disordered, with four C atoms occupying two sets of sites, with a refined occupancy ratio of 0.502 (4):0.498 (4). These two rings are inclined to one another by 85.2 (4)° and to the thiophene ring by 72.7 (3) and 13.0 (3)° for the major and minor components, respectively. In the crystal, molecules are linked via N—H⋯O hydrogen bonds, forming chains along [001]. |
format | Online Article Text |
id | pubmed-4518906 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-45189062015-08-14 Crystal structure of N-[(morpholin-4-yl)(thiophen-2-yl)methyl]benzamide Prabhu, S. Arun Suresh, M. Jameel, A. Abdul Padusha, M. Syed Ali Gunasekaran, B. Acta Crystallogr E Crystallogr Commun Data Reports In the title compound, C(16)H(18)N(2)O(2)S, the morpholine ring adopts a chair conformation. The thiophene ring makes a dihedral angle of 63.54 (14)° with the mean plane of the four C atoms [maximum deviation = 0.010 (3) Å] of the morpholine ring. The benzamide ring is disordered, with four C atoms occupying two sets of sites, with a refined occupancy ratio of 0.502 (4):0.498 (4). These two rings are inclined to one another by 85.2 (4)° and to the thiophene ring by 72.7 (3) and 13.0 (3)° for the major and minor components, respectively. In the crystal, molecules are linked via N—H⋯O hydrogen bonds, forming chains along [001]. International Union of Crystallography 2015-06-20 /pmc/articles/PMC4518906/ /pubmed/26279929 http://dx.doi.org/10.1107/S2056989015011639 Text en © Prabhu et al. 2015 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Data Reports Prabhu, S. Arun Suresh, M. Jameel, A. Abdul Padusha, M. Syed Ali Gunasekaran, B. Crystal structure of N-[(morpholin-4-yl)(thiophen-2-yl)methyl]benzamide |
title | Crystal structure of N-[(morpholin-4-yl)(thiophen-2-yl)methyl]benzamide |
title_full | Crystal structure of N-[(morpholin-4-yl)(thiophen-2-yl)methyl]benzamide |
title_fullStr | Crystal structure of N-[(morpholin-4-yl)(thiophen-2-yl)methyl]benzamide |
title_full_unstemmed | Crystal structure of N-[(morpholin-4-yl)(thiophen-2-yl)methyl]benzamide |
title_short | Crystal structure of N-[(morpholin-4-yl)(thiophen-2-yl)methyl]benzamide |
title_sort | crystal structure of n-[(morpholin-4-yl)(thiophen-2-yl)methyl]benzamide |
topic | Data Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518906/ https://www.ncbi.nlm.nih.gov/pubmed/26279929 http://dx.doi.org/10.1107/S2056989015011639 |
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