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Crystal structure of benzyl 3-oxo-2-oxa-5-aza­bicyclo­[2.2.1]heptane-5-carboxyl­ate

The title compound, C(13)H(13)NO(4) (also known as N-benzyl­oxycarbonyl-4-hy­droxy-l-proline lactone), crystallizes with two mol­ecules in the asymmetric unit. They have slightly different conformations: the fused ring systems almost overlap, but different C—O—C—C torsion angles for the central chai...

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Detalles Bibliográficos
Autores principales: Krishnamurthy, Suvratha, Jalli, Venkataprasad, Vagvala, Tarun Chand, Moriguchi, Tetsuji, Tsuge, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518953/
https://www.ncbi.nlm.nih.gov/pubmed/26279900
http://dx.doi.org/10.1107/S2056989015010464
Descripción
Sumario:The title compound, C(13)H(13)NO(4) (also known as N-benzyl­oxycarbonyl-4-hy­droxy-l-proline lactone), crystallizes with two mol­ecules in the asymmetric unit. They have slightly different conformations: the fused ring systems almost overlap, but different C—O—C—C torsion angles for the central chains of −155.5 (2) and −178.6 (2)° lead to different twists for the terminal benzene ring. In the crystal, the mol­ecules are linked by C—H⋯O inter­actions, generating a three-dimensional network. The absolute structure was established based on an unchanging chiral centre in the synthesis.