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Crystal structure of ethyl 6-chloro­methyl-2-oxo-4-(2,3,4-tri­meth­oxy­phen­yl)-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate

In the title compound, C(17)H(21)ClN(2)O(6), the di­hydro­pyrimidine ring adopts a flattened envelope conformation, with the sp (3)-hybridized C atom forming the flap. The dihedral angle between the least-squares planes of the benzene and di­hydro­pyrimidine rings is 88.09 (6)°. An intra­molecular C...

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Detalles Bibliográficos
Autores principales: Suresh, M., Padusha, M. Syed Ali, Novina, J. Josephine, Vasuki, G., Viswanathan, Vijayan, Velmurugan, Devadasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518964/
https://www.ncbi.nlm.nih.gov/pubmed/26279876
http://dx.doi.org/10.1107/S2056989015011688
Descripción
Sumario:In the title compound, C(17)H(21)ClN(2)O(6), the di­hydro­pyrimidine ring adopts a flattened envelope conformation, with the sp (3)-hybridized C atom forming the flap. The dihedral angle between the least-squares planes of the benzene and di­hydro­pyrimidine rings is 88.09 (6)°. An intra­molecular C—H⋯O hydrogen bond generates an S(6) ring. In the crystal, mol­ecules are linked via pairs of N—H⋯O hydrogen bonds, forming inversion dimers with an R (2) (2)(8) ring motif, and the dimers are linked via further pairs of N—H⋯O hydrogen bonds, forming R (2) (2)(14) rings and chains of mol­ecules along [111]. Pairs of inversion-related chains are linked via weak C—H⋯π inter­actions.