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Atomic structure of anthrax PA pore elucidates toxin translocation

Anthrax toxin, comprising protective antigen (PA), lethal factor (LF) and edema factor (EF), is the major virulence factor of Bacillus anthracis, an agent that causes high mortality in human and animals. PA forms oligomeric prepores that undergo conversion to membrane-spanning pores by endosomal aci...

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Detalles Bibliográficos
Autores principales:	Jiang, Jiansen, Pentelute, Bradley L., Collier, R. John, Zhou, Z. Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519040/ https://www.ncbi.nlm.nih.gov/pubmed/25778700 http://dx.doi.org/10.1038/nature14247

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