Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue

Next Generation Sequencing (NGS) technologies are used to detect somatic mutations in tumors and study germ line variation. Most NGS studies use DNA isolated from whole blood or fresh frozen tissue. However, formalin-fixed paraffin-embedded (FFPE) tissues are one of the most widely available clinica...

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Detalles Bibliográficos
Autores principales: Carrick, Danielle Mercatante, Mehaffey, Michele G., Sachs, Michael C., Altekruse, Sean, Camalier, Corinne, Chuaqui, Rodrigo, Cozen, Wendy, Das, Biswajit, Hernandez, Brenda Y., Lih, Chih-Jian, Lynch, Charles F., Makhlouf, Hala, McGregor, Paul, McShane, Lisa M., Phillips Rohan, JoyAnn, Walsh, William D., Williams, Paul M., Gillanders, Elizabeth M., Mechanic, Leah E., Schully, Sheri D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519244/
https://www.ncbi.nlm.nih.gov/pubmed/26222067
http://dx.doi.org/10.1371/journal.pone.0127353

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