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A TALEN-Exon Skipping Design for a Bethlem Myopathy Model in Zebrafish

Presently, human collagen VI-related diseases such as Ullrich congenital muscular dystrophy (UCMD) and Bethlem myopathy (BM) remain incurable, emphasizing the need to unravel their etiology and improve their treatments. In UCMD, symptom onset occurs early, and both diseases aggravate with ageing. In...

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Detalles Bibliográficos
Autores principales: Radev, Zlatko, Hermel, Jean-Michel, Elipot, Yannick, Bretaud, Sandrine, Arnould, Sylvain, Duchateau, Philippe, Ruggiero, Florence, Joly, Jean-Stéphane, Sohm, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519248/
https://www.ncbi.nlm.nih.gov/pubmed/26221953
http://dx.doi.org/10.1371/journal.pone.0133986