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Non-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and Spleen
B lymphocyte development occurs in the bone marrow, while final differentiation and maturation can occur in both the bone marrow and the spleen. Here we provide evidence that signal regulatory protein α (SIRPα), an Ig-superfamily ITIM-receptor expressed by myeloid but not by lymphoid cells, is invol...
Autores principales: | Kolan, Shrikant Shantilal, Lejon, Kristina, Koskinen Holm, Cecilia, Sulniute, Rima, Lundberg, Pernilla, Matozaki, Takashi, Oldenborg, Per-Arne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519279/ https://www.ncbi.nlm.nih.gov/pubmed/26222253 http://dx.doi.org/10.1371/journal.pone.0134113 |
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