Immunogenicity of the Plasmodium falciparum PfEMP1-VarO Adhesin: Induction of Surface-Reactive and Rosette-Disrupting Antibodies to VarO Infected Erythrocytes

Adhesion of Plasmodium falciparum-infected red blood cells (iRBC) to human erythrocytes (i.e. rosetting) is associated with severe malaria. Rosetting results from interactions between a subset of variant PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1) adhesins and specific erythrocyte...

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Detalles Bibliográficos
Autores principales: Guillotte, Micheline, Juillerat, Alexandre, Igonet, Sébastien, Hessel, Audrey, Petres, Stéphane, Crublet, Elodie, Le Scanf, Cécile, Lewit-Bentley, Anita, Bentley, Graham A., Vigan-Womas, Inès, Mercereau-Puijalon, Odile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519321/
https://www.ncbi.nlm.nih.gov/pubmed/26222304
http://dx.doi.org/10.1371/journal.pone.0134292

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