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A Novel Antiviral Target Structure Involved in the RNA Binding, Dimerization, and Nuclear Export Functions of the Influenza A Virus Nucleoprotein
Developing antiviral therapies for influenza A virus (IAV) infection is an ongoing process because of the rapid rate of antigenic mutation and the emergence of drug-resistant viruses. The ideal strategy is to develop drugs that target well-conserved, functionally restricted, and unique surface struc...
Autores principales: | Kakisaka, Michinori, Sasaki, Yutaka, Yamada, Kazunori, Kondoh, Yasumitsu, Hikono, Hirokazu, Osada, Hiroyuki, Tomii, Kentaro, Saito, Takehiko, Aida, Yoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519322/ https://www.ncbi.nlm.nih.gov/pubmed/26222066 http://dx.doi.org/10.1371/journal.ppat.1005062 |
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