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IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4(+) T Cells and IFN-γ
African trypanosomes are extracellular protozoan parasites causing a chronic debilitating disease associated with a persistent inflammatory response. Maintaining the balance of the inflammatory response via downregulation of activation of M1-type myeloid cells was previously shown to be crucial to a...
Autores principales: | Liu, Gongguan, Xu, Jinjun, Wu, Hui, Sun, Donglei, Zhang, Xiquan, Zhu, Xiaoping, Magez, Stefan, Shi, Meiqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519326/ https://www.ncbi.nlm.nih.gov/pubmed/26222157 http://dx.doi.org/10.1371/journal.ppat.1005065 |
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