Cargando…

Brain Amyloid Deposition and Longitudinal Cognitive Decline in Nondemented Older Subjects: Results from a Multi-Ethnic Population

OBJECTIVE: We aimed to whether the abnormally high amyloid-β (Aβ) level in the brain among apparently healthy elders is related with subtle cognitive deficits and/or accelerated cognitive decline. METHODS: A total of 116 dementia-free participants (mean age 84.5 years) of the Washington Heights Inwo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Yian, Razlighi, Qolamreza R., Zahodne, Laura B., Janicki, Sarah C., Ichise, Masanori, Manly, Jennifer J., Devanand, D. P., Brickman, Adam M., Schupf, Nicole, Mayeux, Richard, Stern, Yaakov
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519341/ https://www.ncbi.nlm.nih.gov/pubmed/26221954 http://dx.doi.org/10.1371/journal.pone.0123743

Ejemplares similares

Predictive utility of task-related functional connectivity vs. voxel activation
por: Habeck, Christian, et al.
Publicado: (2021)

Cognitive Declines Precede and Predict Functional Declines in Aging and Alzheimer’s Disease
por: Zahodne, Laura B., et al.
Publicado: (2013)

Disruption of early visual processing in amyloid-positive healthy individuals and mild cognitive impairment
por: Javitt, Daniel C., et al.
Publicado: (2023)

Unilateral disruptions in the default network with aging in native space
por: Razlighi, Qolamreza R, et al.
Publicado: (2014)

Cortical thickness and its associations with age, total cognition and education across the adult lifespan
por: Habeck, Christian, et al.
Publicado: (2020)

The Effect of Aging on Resting State Connectivity of Predefined Networks in the Brain
por: Varangis, Eleanna, et al.
Publicado: (2019)

Towards an ontology of cognitive processes and their neural substrates: A structural equation modeling approach
por: Eich, Teal, et al.
Publicado: (2020)

Data from a cross-sectional study on Apolipoprotein E (APOE-ε4) and snoring/sleep apnea in non-demented older adults
por: Tsapanou, Angeliki, et al.
Publicado: (2015)

Circulating inflammatory biomarkers are related to cerebrovascular disease in older adults
por: Gu, Yian, et al.
Publicado: (2018)

The Role of Education and Verbal Abilities in Altering the Effect of Age-Related Gray Matter Differences on Cognition
por: Steffener, Jason, et al.
Publicado: (2014)

CHILDHOOD SES AND AGE-RELATED BRAIN CHANGES RACIALLY-ETHNICALLY DIVERSE OLDER ADULTS
por: Turney, Indira C, et al.
Publicado: (2019)

Assessment of Leisure Time Physical Activity and Brain Health in a Multiethnic Cohort of Older Adults
por: Gu, Yian, et al.
Publicado: (2020)

Distinct and joint effects of low and high levels of Aβ and tau deposition on cortical thickness
por: Hani Hojjati, Seyed, et al.
Publicado: (2023)

Functional network mediates age-related differences in reaction time: a replication and extension study
por: Gazes, Yunglin, et al.
Publicado: (2015)

An Inflammation-related Nutrient Pattern is Associated with Both Brain and Cognitive Measures in a Multiethnic Elderly Population
por: Gu, Yian, et al.
Publicado: (2018)

APOE ε4 and resting‐state functional connectivity in racially/ethnically diverse older adults
por: Turney, Indira C., et al.
Publicado: (2020)

Daytime Sleepiness and Sleep Inadequacy as Risk Factors for Dementia
por: Tsapanou, Angeliki, et al.
Publicado: (2015)

Longitudinal trajectory of Amyloid‐related hippocampal subfield atrophy in nondemented elderly
por: Zhang, Liwen, et al.
Publicado: (2020)

Socioeconomic and Psychosocial Mechanisms Underlying Racial and Ethnic Disparities in Cognition Among Older Adults
por: Zahodne, Laura, et al.
Publicado: (2020)

Task-Evoked Negative BOLD Response in the Default Mode Network Does Not Alter Its Functional Connectivity
por: Razlighi, Qolamreza R.
Publicado: (2018)

Differential Association of Geographical Region of Birth With Dementia Risk Across Black Women and Men
por: Avila-Rieger, Justina, et al.
Publicado: (2020)

Association of Regional White Matter Hyperintensities With Longitudinal Alzheimer-Like Pattern of Neurodegeneration in Older Adults
por: Rizvi, Batool, et al.
Publicado: (2021)

Spatial Mutual Information as Similarity Measure for 3-D Brain Image Registration
por: Razlighi, Qolamreza R., et al.
Publicado: (2014)

Landmark‐guided region‐based spatial normalization for functional magnetic resonance imaging
por: He, Hengda, et al.
Publicado: (2022)

Faster Cognitive and Functional Decline in Dysexecutive versus Amnestic Alzheimer's Subgroups: A Longitudinal Analysis of the National Alzheimer's Coordinating Center (NACC) Database
por: Mez, Jesse, et al.
Publicado: (2013)

Effects of Sex, APOE4, and Lifestyle Activities on Cognitive Reserve in Older Adults
por: Pa, Judy, et al.
Publicado: (2022)

The Benefit of Slice Timing Correction in Common fMRI Preprocessing Pipelines
por: Parker, David B., et al.
Publicado: (2019)

Task-evoked Negative BOLD Response and Functional Connectivity in the Default Mode Network are Representative of Two Overlapping but Separate Neurophysiological Processes
por: Parker, David B., et al.
Publicado: (2019)

Reproducibility of serum cytokines in an elderly population
por: Guo, Jing, et al.
Publicado: (2020)

White matter hypointensities and hyperintensities have equivalent correlations with age and CSF β‐amyloid in the nondemented elderly
por: Wei, Ke, et al.
Publicado: (2019)

Plasma p‐tau181, p‐tau217, and other blood‐based Alzheimer's disease biomarkers in a multi‐ethnic, community study
por: Brickman, Adam M., et al.
Publicado: (2021)

Novel image–novel location object recognition task sensitive to age-related cognitive decline in nondemented elderly
por: Haley, Gwendolen E., et al.
Publicado: (2011)

Longitudinal changes in amyloid positron emission tomography and volumetric magnetic resonance imaging in the nondemented Down syndrome population
por: Lao, Patrick J., et al.
Publicado: (2017)

Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population
por: Angevaare, Milou J., et al.
Publicado: (2022)

Brain Amyloid Burden and Resting-State Functional Connectivity in Late Middle-Aged Hispanics
por: Tahmi, Mouna, et al.
Publicado: (2020)

Differences in plasma metabolites related to Alzheimer's disease, APOE ε4 status, and ethnicity
por: Vardarajan, Badri, et al.
Publicado: (2020)

Patterns of cortical thinning in nondemented Parkinson's disease patients
por: Uribe, Carme, et al.
Publicado: (2016)

Evidence suggesting common mechanisms underlie contralateral and ipsilateral negative BOLD responses in the human visual cortex
por: He, Hengda, et al.
Publicado: (2022)

Hearing Loss and Cognitive Decline: Causal Evidence
por: Golub, Justin, et al.
Publicado: (2020)

Antiviral therapy: Valacyclovir Treatment of Alzheimer’s Disease (VALAD) Trial: protocol for a randomised, double-blind, placebo-controlled, treatment trial
por: Devanand, D P, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_488du5ocafj3iva4f7kcm8o7si