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Monocyte:T cell interaction regulates human T cell activation through a CD28/CD46 crosstalk

T cell activation requires engagement of the T cell receptor and of at least one costimulatory molecule. The key role of CD28 in inducing T cell activation has been reported several decades ago and the molecular mechanisms involved well described. The complement regulator CD46 also acts as a costimu...

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Detalles Bibliográficos
Autores principales: Charron, Lauren, Doctrinal, Axelle, Choileain, Siobhan Ni, Astier, Anne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519525/
https://www.ncbi.nlm.nih.gov/pubmed/25787182
http://dx.doi.org/10.1038/icb.2015.42