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Monocyte:T cell interaction regulates human T cell activation through a CD28/CD46 crosstalk
T cell activation requires engagement of the T cell receptor and of at least one costimulatory molecule. The key role of CD28 in inducing T cell activation has been reported several decades ago and the molecular mechanisms involved well described. The complement regulator CD46 also acts as a costimu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519525/ https://www.ncbi.nlm.nih.gov/pubmed/25787182 http://dx.doi.org/10.1038/icb.2015.42 |