Activation of TRESK channels by the inflammatory mediator lysophosphatidic acid balances nociceptive signalling

In dorsal root ganglia (DRG) neurons TRESK channels constitute a major current component of the standing outward current IK(SO). A prominent physiological role of TRESK has been attributed to pain sensation. During inflammation mediators of pain e.g. lysophosphatidic acid (LPA) are released and modu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kollert, Sina, Dombert, Benjamin, Döring, Frank, Wischmeyer, Erhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519772/
https://www.ncbi.nlm.nih.gov/pubmed/26224542
http://dx.doi.org/10.1038/srep12548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519772/
https://www.ncbi.nlm.nih.gov/pubmed/26224542
http://dx.doi.org/10.1038/srep12548

Ejemplares similares