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Activation of TRESK channels by the inflammatory mediator lysophosphatidic acid balances nociceptive signalling

In dorsal root ganglia (DRG) neurons TRESK channels constitute a major current component of the standing outward current IK(SO). A prominent physiological role of TRESK has been attributed to pain sensation. During inflammation mediators of pain e.g. lysophosphatidic acid (LPA) are released and modu...

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Detalles Bibliográficos
Autores principales:	Kollert, Sina, Dombert, Benjamin, Döring, Frank, Wischmeyer, Erhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519772/ https://www.ncbi.nlm.nih.gov/pubmed/26224542 http://dx.doi.org/10.1038/srep12548

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