Selective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage Conversion

Degeneration of midbrain dopaminergic (DA) neurons is a key pathological event of Parkinson’s disease (PD). Limited adult dopaminergic neurogenesis has led to novel therapeutic strategies such as transplantation of dopaminergic precursors (DPs). However, this strategy is currently restrained by a la...

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Detalles Bibliográficos
Autores principales: Tian, Changhai, Li, Yuju, Huang, Yunlong, Wang, Yongxiang, Chen, Dapeng, Liu, Jinxu, Deng, Xiaobei, Sun, Lijun, Anderson, Kristi, Qi, Xinrui, Li, Yulong, Lee Mosley, R., Chen, Xiangmei, Huang, Jian, Zheng, Jialin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519786/
https://www.ncbi.nlm.nih.gov/pubmed/26224135
http://dx.doi.org/10.1038/srep12622

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