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Toll-like receptor 4 signaling in neurons of trigeminal ganglion contributes to nociception induced by acute pulpitis in rats
Pain caused by acute pulpitis (AP) is a common symptom in clinical settings. However, its underlying mechanisms have largely remained unknown. Using AP model, we demonstrated that dental injury caused severe pulp inflammation with up-regulated serum IL-1β. Assessment from head-withdrawal reflex thre...
Autores principales: | Lin, Jia-Ji, Du, Yi, Cai, Wen-Ke, Kuang, Rong, Chang, Ting, Zhang, Zhuo, Yang, Yong-Xiang, Sun, Chao, Li, Zhu-Yi, Kuang, Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519790/ https://www.ncbi.nlm.nih.gov/pubmed/26224622 http://dx.doi.org/10.1038/srep12549 |
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