Cargando…

MiR-21 Protected Cardiomyocytes against Doxorubicin-Induced Apoptosis by Targeting BTG2

Doxorubicin (DOX) is an anthracycline drug with a wide spectrum of antineoplastic activities. However, it causes cardiac cytotoxicity, and this limits its clinical applications. MicroRNA-21 (miR-21) plays a vital role in regulating cell proliferation and apoptosis. While miR-21 is preferentially exp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tong, Zhongyi, Jiang, Bimei, Wu, Yanyang, Liu, Yanjuan, Li, Yuanbin, Gao, Min, Jiang, Yu, Lv, Qinglan, Xiao, Xianzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519855/ https://www.ncbi.nlm.nih.gov/pubmed/26132560 http://dx.doi.org/10.3390/ijms160714511

Ejemplares similares

MicroRNA-126a-5p enhances myocardial ischemia-reperfusion injury through suppressing Hspb8 expression
por: Jiang, Bimei, et al.
Publicado: (2017)

miR-21-5p prevents doxorubicin-induced cardiomyopathy by downregulating BTG2
por: Wang, Qingwei, et al.
Publicado: (2023)

Dexrazoxane Protects Cardiomyocyte from Doxorubicin-Induced Apoptosis by Modulating miR-17-5p
por: Yu, Xiaoxue, et al.
Publicado: (2020)

DSCR9/miR-21-5p axis inhibits pancreatic cancer proliferation and resistance to gemcitabine via BTG2 signaling: DSCR9/miR-21-5p/BTG2 regulates pancreatic cancer
por: Huang, Hui, et al.
Publicado: (2022)

Shenmai injection ameliorates doxorubicin-induced myocardial injury by suppressing autophagy-apoptosis via miR-30a
por: Li, Yanyang, et al.
Publicado: (2023)

Protective effect of miR378* on doxorubicin‐induced cardiomyocyte injury via calumenin
por: Wang, Yu, et al.
Publicado: (2018)

MiR-21 attenuates FAS-mediated cardiomyocyte apoptosis by regulating HIPK3 expression
por: Wang, Xinyu, et al.
Publicado: (2023)

Protective Effect of miR-204 on Doxorubicin-Induced Cardiomyocyte Injury via HMGB1
por: Du, Youyou, et al.
Publicado: (2020)

miR-27a-3p regulates proliferation and apoptosis of colon cancer cells by potentially targeting BTG1
por: Su, Chang, et al.
Publicado: (2019)

Emerging role of antiproliferative protein BTG1 and BTG2
por: Kim, Sang Hyeon, et al.
Publicado: (2022)

Cardiac progenitor cell-derived exosomes prevent cardiomyocytes apoptosis through exosomal miR-21 by targeting PDCD4
por: Xiao, J, et al.
Publicado: (2016)

Autophagy promotes angiogenesis via AMPK/Akt/mTOR signaling during the recovery of heat-denatured endothelial cells
por: Liang, Pengfei, et al.
Publicado: (2018)

Tumor suppressors BTG1 and BTG2: Beyond growth control
por: Yuniati, Laurensia, et al.
Publicado: (2018)

CD47 antibody protects mice from doxorubicin-induced myocardial damage by suppressing cardiomyocyte apoptosis
por: Hao, Yan, et al.
Publicado: (2022)

Icariside II protects cardiomyocytes from hypoxia-induced injury by upregulating the miR-7-5p/BTG2 axis and activating the PI3K/Akt signaling pathway
por: Hu, Dongxia, et al.
Publicado: (2020)

Btg2 is a Negative Regulator of Cardiomyocyte Hypertrophy through a Decrease in Cytosolic RNA
por: Masumura, Yuki, et al.
Publicado: (2016)

MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2
por: Zhou, Lin, et al.
Publicado: (2016)

miR‐15a‐5p and miR‐21‐5p contribute to chemoresistance in cytogenetically normal acute myeloid leukaemia by targeting PDCD4, ARL2 and BTG2
por: Vandewalle, Virginie, et al.
Publicado: (2020)

miR-499-5p Attenuates Mitochondrial Fission and Cell Apoptosis via p21 in Doxorubicin Cardiotoxicity
por: Wan, Qinggong, et al.
Publicado: (2019)

Curcumin Downregulates Phosphate Carrier and Protects against Doxorubicin Induced Cardiomyocyte Apoptosis
por: Junkun, Lu, et al.
Publicado: (2016)

miR-488-3p Protects Cardiomyocytes against Doxorubicin-Induced Cardiotoxicity by Inhibiting CyclinG1
por: Yan, Mingjing, et al.
Publicado: (2022)

LncRNAMORT is upregulated in myocardial infarction and promotes the apoptosis of cardiomyocyte by downregulating miR-93
por: Lv, Jing, et al.
Publicado: (2020)

Atorvastatin protects cardiomyocytes against OGD/R-induced apoptosis by inhibiting miR-199a-5p
por: Li, Yong, et al.
Publicado: (2017)

Atorvastatin protects cardiomyocytes against OGD/R-induced apoptosis by inhibiting miR-199a-5p
por: Li, Yong, et al.
Publicado: (2017)

Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton
por: Tijchon, Esther, et al.
Publicado: (2015)

MiR-25-3p promotes the proliferation of triple negative breast cancer by targeting BTG2
por: Chen, Hua, et al.
Publicado: (2018)

TINCR inhibits the proliferation and invasion of laryngeal squamous cell carcinoma by regulating miR-210/BTG2
por: He, Guoqing, et al.
Publicado: (2021)

Overexpression of angiopoietin-1 reduces doxorubicin-induced apoptosis in cardiomyocytes
por: Ren, Danyang, et al.
Publicado: (2012)

Hydroxytyrosol Prevents Doxorubicin-Induced Oxidative Stress and Apoptosis in Cardiomyocytes
por: Sirangelo, Ivana, et al.
Publicado: (2022)

miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes
por: Qian, Li, et al.
Publicado: (2011)

miR-24 Regulates Intrinsic Apoptosis Pathway in Mouse Cardiomyocytes
por: Wang, Li, et al.
Publicado: (2014)

BTG4 is A Novel p53 Target Gene That Inhibits Cell Growth and Induces Apoptosis
por: Zhang, Na, et al.
Publicado: (2020)

BTG1 potentiates apoptosis and suppresses proliferation in renal cell carcinoma by interacting with PRMT1
por: LIU, CHUNHUI, et al.
Publicado: (2015)

MiR-320 regulates cardiomyocyte apoptosis induced by ischemia–reperfusion injury by targeting AKIP1
por: Tian, Zhi-Qiang, et al.
Publicado: (2018)

miR-153-3p Targets βII Spectrin to Regulate Formaldehyde-Induced Cardiomyocyte Apoptosis
por: Yang, Panyu, et al.
Publicado: (2021)

Protein Methylation and Interaction with the Antiproliferative Gene, BTG2(/TIS21/Pc3)
por: Paik, Woon Ki, et al.
Publicado: (2014)

Long Noncoding RNA SOX2-OT Aggravates Doxorubicin-Induced Apoptosis of Cardiomyocyte by Targeting miR-942-5p/DP5
por: Wang, Haining, et al.
Publicado: (2021)

Down-regulation of BTG1 by miR-454-3p enhances cellular radiosensitivity in renal carcinoma cells
por: Wu, Xin, et al.
Publicado: (2014)

miR-451 Silencing Inhibited Doxorubicin Exposure-Induced Cardiotoxicity in Mice
por: Li, Jun, et al.
Publicado: (2019)

Peroxiredoxin-1 Overexpression Attenuates Doxorubicin-Induced Cardiotoxicity by Inhibiting Oxidative Stress and Cardiomyocyte Apoptosis
por: Jiang, Lai, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4bmog19ejq3043f28mm13e6kl7