Mevalonate Pathway Blockade, Mitochondrial Dysfunction and Autophagy: A Possible Link

The mevalonate pathway, crucial for cholesterol synthesis, plays a key role in multiple cellular processes. Deregulation of this pathway is also correlated with diminished protein prenylation, an important post-translational modification necessary to localize certain proteins, such as small GTPases,...

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Detalles Bibliográficos
Autores principales: Tricarico, Paola Maura, Crovella, Sergio, Celsi, Fulvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519939/
https://www.ncbi.nlm.nih.gov/pubmed/26184189
http://dx.doi.org/10.3390/ijms160716067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519939/
https://www.ncbi.nlm.nih.gov/pubmed/26184189
http://dx.doi.org/10.3390/ijms160716067

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