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Sequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic Landscapes

Ewing sarcoma is an aggressive neoplasm occurring predominantly in adolescent Caucasians. At the genome level, a pathognomonic EWSR1-ETS translocation is present. The resulting fusion protein acts as a molecular driver in the tumor development and interferes, amongst others, with endogenous transcri...

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Detalles Bibliográficos
Autores principales:	Sand, Laurens G. L., Szuhai, Karoly, Hogendoorn, Pancras C. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519945/ https://www.ncbi.nlm.nih.gov/pubmed/26193259 http://dx.doi.org/10.3390/ijms160716176

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