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A New Ligustrazine Derivative-Selective Cytotoxicity by Suppression of NF-κB/p65 and COX-2 Expression on Human Hepatoma Cells. Part 3
A new anticancer ligustrazine derivative, 3β-hydroxyolea-12-en-28-oic acid-3,5,6-trimethylpyrazin-2-methylester (T-OA, C(38)H(58)O(3)N(2)), was previously reported. It was synthesized via conjugating hepatoprotective and anticancer ingredients of traditional Chinese medicine. We found that T-OA exer...
Autores principales: | Zhang, Chenze, Yan, Wenqiang, Li, Bi, Xu, Bing, Gong, Yan, Chu, Fuhao, Zhang, Yuzhong, Yao, Qiuli, Wang, Penglong, Lei, Haimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519956/ https://www.ncbi.nlm.nih.gov/pubmed/26193270 http://dx.doi.org/10.3390/ijms160716401 |
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