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Properties of the Mechanosensitive Channel MscS Pore Revealed by Tryptophan Scanning Mutagenesis

[Image: see text] Bacterial mechanosensitive channels gate when the transmembrane turgor rises to levels that compromise the structural integrity of the cell wall. Gating creates a transient large diameter pore that allows hydrated solutes to pass from the cytoplasm at rates close to those of diffus...

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Detalles Bibliográficos
Autores principales:	Rasmussen, Tim, Rasmussen, Akiko, Singh, Shivani, Galbiati, Heloisa, Edwards, Michelle D., Miller, Samantha, Booth, Ian R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519979/ https://www.ncbi.nlm.nih.gov/pubmed/26126964 http://dx.doi.org/10.1021/acs.biochem.5b00294

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