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Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition
Changes in cell fate and identity are essential for endothelial-to-haematopoietic transition (EHT), an embryonic process that generates the first adult populations of haematopoietic stem cells (HSCs) from hemogenic endothelial cells. Dissecting EHT regulation is a critical step towards the productio...
Autores principales: | Lizama, Carlos O., Hawkins, John S., Schmitt, Christopher E., Bos, Frank L., Zape, Joan P., Cautivo, Kelly M., Borges Pinto, Hugo, Rhyner, Alexander M., Yu, Hui, Donohoe, Mary E., Wythe, Joshua D., Zovein, Ann C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519987/ https://www.ncbi.nlm.nih.gov/pubmed/26204127 http://dx.doi.org/10.1038/ncomms8739 |
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