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Predicting the combined effect of multiple genetic variants

BACKGROUND: Many genetic variants have been identified in the human genome. The functional effects of a single variant have been intensively studied. However, the joint effects of multiple variants in the same genes have been largely ignored due to their complexity or lack of data. This paper uses H...

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Detalles Bibliográficos
Autores principales:	Liu, Mingming, Watson, Layne T., Zhang, Liqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520001/ https://www.ncbi.nlm.nih.gov/pubmed/26223264 http://dx.doi.org/10.1186/s40246-015-0040-4

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