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The quality of economic evaluations of ultra-orphan drugs in Europe – a systematic review
An orphan disease is defined in the EU as a disorder affecting less than 1 in 2 000 individuals. The concept of ultra-orphan has been proposed for diseases with a prevalence of less than 1:50 000. Drugs for ultra-orphan diseases are amongst the most expensive medicines on a cost-per-patient basis. T...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520069/ https://www.ncbi.nlm.nih.gov/pubmed/26223689 http://dx.doi.org/10.1186/s13023-015-0305-y |