Restoration of Epigenetically Silenced Sulfatase 1 Expression by 5-Aza-2′-Deoxycytidine Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy-Induced Apoptosis

BACKGROUND: Hepatocellular carcinoma (HCC) is the second most frequent cause of cancer death worldwide. Sulfatase 1 (SULF1) functions as a tumor suppressor in HCC cell lines in vitro but also has an oncogenic effect in some HCCs in vivo. AIM: The purpose of this study was to examine the mechanisms r...

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Detalles Bibliográficos
Autores principales: Shire, Abdirashid, Lomberk, Gwen, Lai, Jin-Ping, Zou, Hongzhi, Tsuchiya, Norihiko, Aderca, Ileana, Moser, Catherine D., Gulaid, Kadra H., Oseini, Abdul, Hu, Chunling, Warsame, Omar, Jenkins, Robert B., Roberts, Lewis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520440/
https://www.ncbi.nlm.nih.gov/pubmed/26236329
http://dx.doi.org/10.1159/000375461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520440/
https://www.ncbi.nlm.nih.gov/pubmed/26236329
http://dx.doi.org/10.1159/000375461

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