All-Trans Retinoic Acid Induces TGF-β(2) in Intestinal Epithelial Cells via RhoA- and p38α MAPK-Mediated Activation of the Transcription Factor ATF2

OBJECTIVE: We have shown previously that preterm infants are at risk of necrotizing enterocolitis (NEC), an inflammatory bowel necrosis typically seen in infants born prior to 32 weeks’ gestation, because of the developmental deficiency of transforming growth factor (TGF)-β(2) in the intestine. The...

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Detalles Bibliográficos
Autores principales: Namachivayam, Kopperuncholan, MohanKumar, Krishnan, Arbach, Dima, Jagadeeswaran, Ramasamy, Jain, Sunil K., Natarajan, Viswanathan, Mehta, Dolly, Jankov, Robert P., Maheshwari, Akhil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520553/
https://www.ncbi.nlm.nih.gov/pubmed/26225425
http://dx.doi.org/10.1371/journal.pone.0134003

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