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Association of V(H)4-59 Antibody Variable Gene Usage with Recognition of an Immunodominant Epitope on the HIV-1 Gag Protein

The human antibody response against HIV-1 infection recognizes diverse antigenic subunits of the virion, and includes a high level of antibodies to the Gag protein. We report here the isolation and characterization of a subset of Gag-specific human monoclonal antibodies (mAbs) that were prevalent in...

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Detalles Bibliográficos
Autores principales: Chukwuma, Valentine U., Hicar, Mark D., Chen, Xuemin, Nicholas, Katherine J., Joyner, Amanda, Kalams, Spyros A., Landucci, Gary, Forthal, Donald N., Spearman, Paul W., Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520566/
https://www.ncbi.nlm.nih.gov/pubmed/26226263
http://dx.doi.org/10.1371/journal.pone.0133509