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Processive ATP-driven Substrate Disassembly by the N-Ethylmaleimide-sensitive Factor (NSF) Molecular Machine

SNARE proteins promote membrane fusion by forming a four-stranded parallel helical bundle that brings the membranes into close proximity. Post-fusion, the complex is disassembled by an AAA+ ATPase called N-ethylmaleimide-sensitive factor (NSF). We present evidence that NSF uses a processive unwindin...

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Detalles Bibliográficos
Autores principales:	Cipriano, Daniel J., Jung, Jaemyeong, Vivona, Sandro, Fenn, Timothy D., Brunger, Axel T., Bryant, Zev
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Membrane Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520572/ https://www.ncbi.nlm.nih.gov/pubmed/23775070 http://dx.doi.org/10.1074/jbc.M113.476705

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