Essential and Checkpoint Functions of Budding Yeast ATM and ATR during Meiotic Prophase Are Facilitated by Differential Phosphorylation of a Meiotic Adaptor Protein, Hop1

A hallmark of the conserved ATM/ATR signalling is its ability to mediate a wide range of functions utilizing only a limited number of adaptors and effector kinases. During meiosis, Tel1 and Mec1, the budding yeast ATM and ATR, respectively, rely on a meiotic adaptor protein Hop1, a 53BP1/Rad9 functi...

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Detalles Bibliográficos
Autores principales: Penedos, Ana, Johnson, Anthony L., Strong, Emily, Goldman, Alastair S., Carballo, Jesús A., Cha, Rita S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520594/
https://www.ncbi.nlm.nih.gov/pubmed/26225562
http://dx.doi.org/10.1371/journal.pone.0134297

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