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Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases

[Image: see text] Several naturally occurring dietary polyphenols with chemopreventive or anticancer properties are topoisomerase II poisons. To identify additional phytochemicals that enhance topoisomerase II-mediated DNA cleavage, a library of 341 Mediterranean plant extracts was screened for acti...

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Detalles Bibliográficos
Autores principales:	Vann, Kendra R., Sedgeman, Carl A., Gopas, Jacob, Golan-Goldhirsh, Avi, Osheroff, Neil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520624/ https://www.ncbi.nlm.nih.gov/pubmed/26132160 http://dx.doi.org/10.1021/acs.biochem.5b00162

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