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Thermodynamic Switch in Binding of Adhesion/Growth Regulatory Human Galectin-3 to Tumor-Associated TF Antigen (CD176) and MUC1 Glycopeptides

[Image: see text] A shift to short-chain glycans is an observed change in mucin-type O-glycosylation in premalignant and malignant epithelia. Given the evidence that human galectin-3 can interact with mucins and also weakly with free tumor-associated Thomsen-Friedenreich (TF) antigen (CD176), the st...

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Detalles Bibliográficos
Autores principales:	Rodriguez, Maria C., Yegorova, Svetlana, Pitteloud, Jean-Philippe, Chavaroche, Anais E., André, Sabine, Ardá, Ana, Minond, Dimitriy, Jiménez-Barbero, Jesús, Gabius, Hans-Joachim, Cudic, Mare
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520625/ https://www.ncbi.nlm.nih.gov/pubmed/26129647 http://dx.doi.org/10.1021/acs.biochem.5b00555

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