Cellular and molecular determinants of all-trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression

Forty-two cell lines recapitulating mammary carcinoma heterogeneity were profiled for all-trans retinoic acid (ATRA) sensitivity. Luminal and ER(+) (estrogen-receptor-positive) cell lines are generally sensitive to ATRA, while refractoriness/low sensitivity is associated with a Basal phenotype and H...

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Detalles Bibliográficos
Autores principales: Centritto, Floriana, Paroni, Gabriela, Bolis, Marco, Garattini, Silvio Ken, Kurosaki, Mami, Barzago, Maria Monica, Zanetti, Adriana, Fisher, James Neil, Scott, Mark Francis, Pattini, Linda, Lupi, Monica, Ubezio, Paolo, Piccotti, Francesca, Zambelli, Alberto, Rizzo, Paola, Gianni', Maurizio, Fratelli, Maddalena, Terao, Mineko, Garattini, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520659/
https://www.ncbi.nlm.nih.gov/pubmed/25888236
http://dx.doi.org/10.15252/emmm.201404670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520659/
https://www.ncbi.nlm.nih.gov/pubmed/25888236
http://dx.doi.org/10.15252/emmm.201404670

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