A method to predict the impact of regulatory variants from DNA sequence

Most variants implicated in common human disease by Genome-Wide Association Studies (GWAS) lie in non-coding sequence intervals. Despite the suggestion that regulatory element disruption represents a common theme, identifying causal risk variants within indicted genomic regions remains a significant...

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Detalles Bibliográficos
Autores principales: Lee, Dongwon, Gorkin, David U., Baker, Maggie, Strober, Benjamin J., Asoni, Alessandro L., McCallion, Andrew S., Beer, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520745/
https://www.ncbi.nlm.nih.gov/pubmed/26075791
http://dx.doi.org/10.1038/ng.3331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520745/
https://www.ncbi.nlm.nih.gov/pubmed/26075791
http://dx.doi.org/10.1038/ng.3331

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