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Rare benign pleomorphic adenoma of the nose: short study and literature review
Pleomorphic adenoma is one of the most common benign tumors of the major salivary glands. It can also occur in the minor salivary glands, which exist in the nasal cavity. Intranasal pleomorphic adenoma usually originates from glands of the nasal septum mucosa. We present the results of endoscopic en...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520830/ https://www.ncbi.nlm.nih.gov/pubmed/26240639 http://dx.doi.org/10.5114/wiitm.2014.47370 |
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author | Wierzchowska, Małgorzata Bodnar, Magdalena Burduk, Paweł K. Kaźmierczak, Wojciech Marszałek, Andrzej |
author_facet | Wierzchowska, Małgorzata Bodnar, Magdalena Burduk, Paweł K. Kaźmierczak, Wojciech Marszałek, Andrzej |
author_sort | Wierzchowska, Małgorzata |
collection | PubMed |
description | Pleomorphic adenoma is one of the most common benign tumors of the major salivary glands. It can also occur in the minor salivary glands, which exist in the nasal cavity. Intranasal pleomorphic adenoma usually originates from glands of the nasal septum mucosa. We present the results of endoscopic endonasal surgery of this pathology. The aim of the study was to present the endoscopic technique for nasal septum pleomorphic adenoma surgery. The retrospective examination of 3 patients was performed. There were 2 women and 1 man. Age ranged from 15 to 46 years. All the patients presented with nasal obstruction and occasional epistaxis for at least for 6 months. We performed endoscopic surgery to remove the tumors. In all cases we dissected the septal perichondrium to achieved free margins of the tumor. The microscopic examination revealed an epithelial and myoepithelial component with tubular structures composed of two cell layers, ducts, and a solid area found in a loose myxochondroid area. Additionally, immunohistochemical staining was performed using antibodies against cytokeratin, Ki-67, and vimentin. Patients’ postoperative course was uneventful, and no complications were encountered. No recurrence was present during patients’ postoperative visits. Nasal benign pleomorphic adenoma is a rare tumor which should be taken into consideration in the nasal cavity during surgery. The correct histological diagnosis can be confirmed by additional histological studies. Endoscopic endonasal surgery is reserved for small tumors. |
format | Online Article Text |
id | pubmed-4520830 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-45208302015-08-03 Rare benign pleomorphic adenoma of the nose: short study and literature review Wierzchowska, Małgorzata Bodnar, Magdalena Burduk, Paweł K. Kaźmierczak, Wojciech Marszałek, Andrzej Wideochir Inne Tech Maloinwazyjne Case Report Pleomorphic adenoma is one of the most common benign tumors of the major salivary glands. It can also occur in the minor salivary glands, which exist in the nasal cavity. Intranasal pleomorphic adenoma usually originates from glands of the nasal septum mucosa. We present the results of endoscopic endonasal surgery of this pathology. The aim of the study was to present the endoscopic technique for nasal septum pleomorphic adenoma surgery. The retrospective examination of 3 patients was performed. There were 2 women and 1 man. Age ranged from 15 to 46 years. All the patients presented with nasal obstruction and occasional epistaxis for at least for 6 months. We performed endoscopic surgery to remove the tumors. In all cases we dissected the septal perichondrium to achieved free margins of the tumor. The microscopic examination revealed an epithelial and myoepithelial component with tubular structures composed of two cell layers, ducts, and a solid area found in a loose myxochondroid area. Additionally, immunohistochemical staining was performed using antibodies against cytokeratin, Ki-67, and vimentin. Patients’ postoperative course was uneventful, and no complications were encountered. No recurrence was present during patients’ postoperative visits. Nasal benign pleomorphic adenoma is a rare tumor which should be taken into consideration in the nasal cavity during surgery. The correct histological diagnosis can be confirmed by additional histological studies. Endoscopic endonasal surgery is reserved for small tumors. Termedia Publishing House 2014-12-04 2015-07 /pmc/articles/PMC4520830/ /pubmed/26240639 http://dx.doi.org/10.5114/wiitm.2014.47370 Text en Copyright © 2015 Sekcja Wideochirurgii TChP http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Wierzchowska, Małgorzata Bodnar, Magdalena Burduk, Paweł K. Kaźmierczak, Wojciech Marszałek, Andrzej Rare benign pleomorphic adenoma of the nose: short study and literature review |
title | Rare benign pleomorphic adenoma of the nose: short study and literature review |
title_full | Rare benign pleomorphic adenoma of the nose: short study and literature review |
title_fullStr | Rare benign pleomorphic adenoma of the nose: short study and literature review |
title_full_unstemmed | Rare benign pleomorphic adenoma of the nose: short study and literature review |
title_short | Rare benign pleomorphic adenoma of the nose: short study and literature review |
title_sort | rare benign pleomorphic adenoma of the nose: short study and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520830/ https://www.ncbi.nlm.nih.gov/pubmed/26240639 http://dx.doi.org/10.5114/wiitm.2014.47370 |
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