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Rare benign pleomorphic adenoma of the nose: short study and literature review

Pleomorphic adenoma is one of the most common benign tumors of the major salivary glands. It can also occur in the minor salivary glands, which exist in the nasal cavity. Intranasal pleomorphic adenoma usually originates from glands of the nasal septum mucosa. We present the results of endoscopic en...

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Autores principales: Wierzchowska, Małgorzata, Bodnar, Magdalena, Burduk, Paweł K., Kaźmierczak, Wojciech, Marszałek, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520830/
https://www.ncbi.nlm.nih.gov/pubmed/26240639
http://dx.doi.org/10.5114/wiitm.2014.47370
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author Wierzchowska, Małgorzata
Bodnar, Magdalena
Burduk, Paweł K.
Kaźmierczak, Wojciech
Marszałek, Andrzej
author_facet Wierzchowska, Małgorzata
Bodnar, Magdalena
Burduk, Paweł K.
Kaźmierczak, Wojciech
Marszałek, Andrzej
author_sort Wierzchowska, Małgorzata
collection PubMed
description Pleomorphic adenoma is one of the most common benign tumors of the major salivary glands. It can also occur in the minor salivary glands, which exist in the nasal cavity. Intranasal pleomorphic adenoma usually originates from glands of the nasal septum mucosa. We present the results of endoscopic endonasal surgery of this pathology. The aim of the study was to present the endoscopic technique for nasal septum pleomorphic adenoma surgery. The retrospective examination of 3 patients was performed. There were 2 women and 1 man. Age ranged from 15 to 46 years. All the patients presented with nasal obstruction and occasional epistaxis for at least for 6 months. We performed endoscopic surgery to remove the tumors. In all cases we dissected the septal perichondrium to achieved free margins of the tumor. The microscopic examination revealed an epithelial and myoepithelial component with tubular structures composed of two cell layers, ducts, and a solid area found in a loose myxochondroid area. Additionally, immunohistochemical staining was performed using antibodies against cytokeratin, Ki-67, and vimentin. Patients’ postoperative course was uneventful, and no complications were encountered. No recurrence was present during patients’ postoperative visits. Nasal benign pleomorphic adenoma is a rare tumor which should be taken into consideration in the nasal cavity during surgery. The correct histological diagnosis can be confirmed by additional histological studies. Endoscopic endonasal surgery is reserved for small tumors.
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spelling pubmed-45208302015-08-03 Rare benign pleomorphic adenoma of the nose: short study and literature review Wierzchowska, Małgorzata Bodnar, Magdalena Burduk, Paweł K. Kaźmierczak, Wojciech Marszałek, Andrzej Wideochir Inne Tech Maloinwazyjne Case Report Pleomorphic adenoma is one of the most common benign tumors of the major salivary glands. It can also occur in the minor salivary glands, which exist in the nasal cavity. Intranasal pleomorphic adenoma usually originates from glands of the nasal septum mucosa. We present the results of endoscopic endonasal surgery of this pathology. The aim of the study was to present the endoscopic technique for nasal septum pleomorphic adenoma surgery. The retrospective examination of 3 patients was performed. There were 2 women and 1 man. Age ranged from 15 to 46 years. All the patients presented with nasal obstruction and occasional epistaxis for at least for 6 months. We performed endoscopic surgery to remove the tumors. In all cases we dissected the septal perichondrium to achieved free margins of the tumor. The microscopic examination revealed an epithelial and myoepithelial component with tubular structures composed of two cell layers, ducts, and a solid area found in a loose myxochondroid area. Additionally, immunohistochemical staining was performed using antibodies against cytokeratin, Ki-67, and vimentin. Patients’ postoperative course was uneventful, and no complications were encountered. No recurrence was present during patients’ postoperative visits. Nasal benign pleomorphic adenoma is a rare tumor which should be taken into consideration in the nasal cavity during surgery. The correct histological diagnosis can be confirmed by additional histological studies. Endoscopic endonasal surgery is reserved for small tumors. Termedia Publishing House 2014-12-04 2015-07 /pmc/articles/PMC4520830/ /pubmed/26240639 http://dx.doi.org/10.5114/wiitm.2014.47370 Text en Copyright © 2015 Sekcja Wideochirurgii TChP http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Wierzchowska, Małgorzata
Bodnar, Magdalena
Burduk, Paweł K.
Kaźmierczak, Wojciech
Marszałek, Andrzej
Rare benign pleomorphic adenoma of the nose: short study and literature review
title Rare benign pleomorphic adenoma of the nose: short study and literature review
title_full Rare benign pleomorphic adenoma of the nose: short study and literature review
title_fullStr Rare benign pleomorphic adenoma of the nose: short study and literature review
title_full_unstemmed Rare benign pleomorphic adenoma of the nose: short study and literature review
title_short Rare benign pleomorphic adenoma of the nose: short study and literature review
title_sort rare benign pleomorphic adenoma of the nose: short study and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520830/
https://www.ncbi.nlm.nih.gov/pubmed/26240639
http://dx.doi.org/10.5114/wiitm.2014.47370
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