Cargando…

Conus Medullaris Teratoma with Utilization of Fiber Tractography: Case Report

Objective Conus medullaris teratomas are very rare tumors. Traditional preoperative diagnosis depended on the findings from magnetic resonance imaging (MRI). Tractography is a novel technique that has recently been utilized to diagnose spinal cord lesions. This case report shows that fiber tractogra...

Descripción completa

Detalles Bibliográficos
Autores principales: Alkherayf, Fahad, Arab, Abdullah Faisal, Tsai, Eve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521003/
https://www.ncbi.nlm.nih.gov/pubmed/26251802
http://dx.doi.org/10.1055/s-0035-1555134
_version_ 1782383746772631552
author Alkherayf, Fahad
Arab, Abdullah Faisal
Tsai, Eve
author_facet Alkherayf, Fahad
Arab, Abdullah Faisal
Tsai, Eve
author_sort Alkherayf, Fahad
collection PubMed
description Objective Conus medullaris teratomas are very rare tumors. Traditional preoperative diagnosis depended on the findings from magnetic resonance imaging (MRI). Tractography is a novel technique that has recently been utilized to diagnose spinal cord lesions. This case report shows that fiber tractography has great potential in preoperative diagnosis and postoperative follow-up of teratomas of the conus medullaris. Methods A 50-year-old man with a conus medullaris teratoma underwent tractography with the aim of visualizing the tumor in relation to the white matter tracts. The patient underwent a T12–L2 laminectomy, and the lesion was resected. The histopathology diagnosis was of a mature teratoma. Study Design Case report. Results Diffusion tensor imaging (DTI) and tractography provide more details about the white matter tracts in relation to space-occupying lesions that may be more sensitive than conventional MRI and have recently been utilized in spinal cord lesions. Fiber tracking has the ability to visualize the integrity of the white matter tracts at the level of the conus medullaris in relation to the lesion. The tracts appeared to be displaced by the lesion at the conus medullaris. Tractography also showed no white matter tracts within the lesion. Such findings are consistent with the characteristics of a benign lesion. Exploiting tractography in this case was helpful in predicting the nature of the lesion preoperatively and in planning the surgical intervention. Conclusions Conus medullaris teratomas mostly affect adults. Patients generally present with a long history of clinical symptoms prior to diagnosis. Surgery is required for diagnosis, and the goal should be complete tumor excision without sacrificing any neurologic functions. The use of DTI and tractography, in addition to conventional MRI, has the potential to be very valuable for the diagnosis, surgical planning, and follow-up of patients with conus medullaris teratomas.
format Online
Article
Text
id pubmed-4521003
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Georg Thieme Verlag KG
record_format MEDLINE/PubMed
spelling pubmed-45210032015-08-06 Conus Medullaris Teratoma with Utilization of Fiber Tractography: Case Report Alkherayf, Fahad Arab, Abdullah Faisal Tsai, Eve J Neurol Surg Rep Article Objective Conus medullaris teratomas are very rare tumors. Traditional preoperative diagnosis depended on the findings from magnetic resonance imaging (MRI). Tractography is a novel technique that has recently been utilized to diagnose spinal cord lesions. This case report shows that fiber tractography has great potential in preoperative diagnosis and postoperative follow-up of teratomas of the conus medullaris. Methods A 50-year-old man with a conus medullaris teratoma underwent tractography with the aim of visualizing the tumor in relation to the white matter tracts. The patient underwent a T12–L2 laminectomy, and the lesion was resected. The histopathology diagnosis was of a mature teratoma. Study Design Case report. Results Diffusion tensor imaging (DTI) and tractography provide more details about the white matter tracts in relation to space-occupying lesions that may be more sensitive than conventional MRI and have recently been utilized in spinal cord lesions. Fiber tracking has the ability to visualize the integrity of the white matter tracts at the level of the conus medullaris in relation to the lesion. The tracts appeared to be displaced by the lesion at the conus medullaris. Tractography also showed no white matter tracts within the lesion. Such findings are consistent with the characteristics of a benign lesion. Exploiting tractography in this case was helpful in predicting the nature of the lesion preoperatively and in planning the surgical intervention. Conclusions Conus medullaris teratomas mostly affect adults. Patients generally present with a long history of clinical symptoms prior to diagnosis. Surgery is required for diagnosis, and the goal should be complete tumor excision without sacrificing any neurologic functions. The use of DTI and tractography, in addition to conventional MRI, has the potential to be very valuable for the diagnosis, surgical planning, and follow-up of patients with conus medullaris teratomas. Georg Thieme Verlag KG 2015-06-12 2015-07 /pmc/articles/PMC4521003/ /pubmed/26251802 http://dx.doi.org/10.1055/s-0035-1555134 Text en © Thieme Medical Publishers
spellingShingle Article
Alkherayf, Fahad
Arab, Abdullah Faisal
Tsai, Eve
Conus Medullaris Teratoma with Utilization of Fiber Tractography: Case Report
title Conus Medullaris Teratoma with Utilization of Fiber Tractography: Case Report
title_full Conus Medullaris Teratoma with Utilization of Fiber Tractography: Case Report
title_fullStr Conus Medullaris Teratoma with Utilization of Fiber Tractography: Case Report
title_full_unstemmed Conus Medullaris Teratoma with Utilization of Fiber Tractography: Case Report
title_short Conus Medullaris Teratoma with Utilization of Fiber Tractography: Case Report
title_sort conus medullaris teratoma with utilization of fiber tractography: case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521003/
https://www.ncbi.nlm.nih.gov/pubmed/26251802
http://dx.doi.org/10.1055/s-0035-1555134
work_keys_str_mv AT alkherayffahad conusmedullaristeratomawithutilizationoffibertractographycasereport
AT arababdullahfaisal conusmedullaristeratomawithutilizationoffibertractographycasereport
AT tsaieve conusmedullaristeratomawithutilizationoffibertractographycasereport