Axonal protection by brimonidine with modulation of p62 expression in TNF-induced optic nerve degeneration

PURPOSE: The p62, also called sequestosome 1 (SQSTM1), plays a crucial role in tumor necrosis factor (TNF)-induced optic nerve degeneration. Brimonidine has been shown to have protective effects on retinal ganglion cell bodies, although its role in their axons remains to be examined. We determined w...

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Detalles Bibliográficos
Autores principales: Kitaoka, Yasushi, Kojima, Kaori, Munemasa, Yasunari, Sase, Kana, Takagi, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521096/
https://www.ncbi.nlm.nih.gov/pubmed/25863674
http://dx.doi.org/10.1007/s00417-015-3005-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521096/
https://www.ncbi.nlm.nih.gov/pubmed/25863674
http://dx.doi.org/10.1007/s00417-015-3005-3

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