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Axonal protection by brimonidine with modulation of p62 expression in TNF-induced optic nerve degeneration
PURPOSE: The p62, also called sequestosome 1 (SQSTM1), plays a crucial role in tumor necrosis factor (TNF)-induced optic nerve degeneration. Brimonidine has been shown to have protective effects on retinal ganglion cell bodies, although its role in their axons remains to be examined. We determined w...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521096/ https://www.ncbi.nlm.nih.gov/pubmed/25863674 http://dx.doi.org/10.1007/s00417-015-3005-3 |